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Title 

Eudesmanolides from Taraxacum mongolicum and their inhibitory effects on the production of nitric oxide

Authors 

Y H KimS J ChooIn Ja RyooJong Seog AhnIck-Dong Yoo

Publisher 

Pharmaceutical Society of Korea

Issue Date 

2011

Citation 

Archives of Pharmacal Research, vol. 34, no. 1, pp. 37-41

Keywords 

EudesmanolideMacrophageNitric oxideTaraxacum mongolicum

Abstract 

A new eudesmanolide, 1β,3β-dihydroxy-eudesman-11(13)-en-6α, 12-olide (1) was isolated and identified from Taraxacum mongolicum, together with two known compounds, 1β,3β-dihydroxyeudesman-6α,12-olide (2) and loliolide (3). The structure of 1 was established by analysis of its physical and spectroscopic data. 1 was found to have an inhibitory activity on nitric oxide production with an IC50 of 38.9 μM in activated RAW 264.7 cells.

ISSN 

0253-6269

Link 

http://dx.doi.org/10.1007/s12272-011-0104-5

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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