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Title 

Antibacterial polyketides from the jellyfish-derived fungus Paecilomyces variotii

Authors 

J LiuF LiE L KimJ L LiJ HongKyung Sook BaeH Y ChungH S KimJ H Jung

Publisher 

American Chemical Society

Issue Date 

2011

Citation 

Journal of Natural Products, vol. 74, no. 8, pp. 1826-1829

Abstract 

Four new polyketides (1-4) were isolated from the fungus Paecilomyces variotii, which was derived from the jellyfish Nemopilema nomurai. The planar structures and relative configurations of these polyketides were elucidated on the basis of spectroscopic analyses, including 2D NMR experiments. The compounds showed inhibitory activity against pathogenic bacteria including methicillin-resistant Staphylococcus aureus 3089 and multi-drug-resistant Vibrio parahemolyticus 7001 with MIC values in the range 5-40 μg/mL.

ISSN 

0163-3864

Link 

http://dx.doi.org/10.1021/np200350b

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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