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Title 

Syntheses of sulfur and selenium analogues of pachastrissamine via double displacements of cyclic sulfate

 

고리형 설페이트의 이중 치환을 이용한 파카스크리사민 유도체의 합성

Authors 

H JeonH BaeD J BaekYoung Shin KwakD KimS Kim

Publisher 

Royal Society of Chemistry

Issue Date 

2011

Citation 

Organic & Biomolecular Chemistry, vol. 9, no. 20, pp. 7237-7242

Abstract 

Bioisosteric analogues of pachastrissamine that contain sulfur and selenium atoms replacing the oxygen in the ring system, were efficiently prepared from a cyclic sulfate intermediate by sequential intermolecular and intramolecular S N2 displacement reactions of the dianions. The analogues exhibited cytotoxicities comparable to that of pachastrissamine.

ISSN 

1477-0520

Link 

http://dx.doi.org/10.1039/c1ob05920c

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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