상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

Cytotoxic terpenes from the stems of Dipterocarpus obtusifolius collected in Cambodia

 

디프테로카퍼스옵투시폴리우스로부터 분리한 세포독성을 갖는 테르펜 화합물

Authors 

P KhievOk-Kyoung KwonHyuk Hwan SongSei Ryang OhKyung Seop AhnHyeong Kyu LeeY W Chin

Publisher 

Pharmaceutical Society of Japan

Issue Date 

2012

Citation 

Chemical & Pharmaceutical Bulletin, vol. 60, no. 8, pp. 955-961

Keywords 

CytotoxicityDipterocarpaceaeDipterocarpus obtusifoliusTerpene

Abstract 

From the stems of Dipterocarpus obtusifolius, five new triterpenes, 3-oxo-20-hydroxy-30α-methyl,17(29)-α-epoxy-28-norlupane (1), 3-oxo-20-hydroxy-30β-methyl-17(29)α-epoxy-28-norlupane (2), 3,20-dioxo-28,29-norlupan-17α-ol (3), 27-demethyl-20(S)-dammar-23-ene-20- ol-3,25-dione (4), and 3-epi-cecropic acid (5) together with 13 known compounds including diterpene, sesquiterpenes and triterpenes were isolated and characterized. All isolates were tested for their cytotoxicities against a small panel of human cancer cell lines. Of the tested compounds, compounds 4-11 were found to be cytotoxic against one or more human cancer cell lines.

ISSN 

0009-2363

Link 

http://dx.doi.org/10.1248/cpb.c12-00012

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


Files in This Item: SizeFormat
10894.pdf715KbAdobe PDF
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)