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Title 

A novel therapeutic target, GPR43: where it stands in drug discovery

 

신약 타겟 GPR43

Authors 

Sunhong KimY M KimYoung Shin Kwak

Publisher 

Pharmaceutical Society of Korea

Issue Date 

2012

Citation 

Archives of Pharmacal Research, vol. 35, no. 9, pp. 1505-1509

Abstract 

With growing interest in human microbiome for its implication in metabolic disorders, inflammatory diseases, immune disorders and so forth, understanding the biology at the interface of the gut flora and the host becomes very important for identifying novel therapeutic avenues. GPR43 has been deorphanized and the metabolites of microbiome, such as short-chain fatty acids, serve as its natural ligands. There are numerous reports that GPR43 might be a crucial link to the novel therapies for the unmet medical needs and many drug discovery organizations are making their moves in response.

ISSN 

0253-6269

Link 

http://dx.doi.org/10.1007/s12272-012-0900-6

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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