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Title 

Cytotoxic petrosiacetylenes from the marine sponge Petrosia sp.

 

해양 sponge Petrosia sp.에서 추출한 petrosiacetylenes의 세포 독성 효과

Authors 

Y J LeeS J YooJong Soon KangJi Eun YunH J ShinJ S LeeH S Lee

Publisher 

Springer Verlag (Germany)

Issue Date 

2013

Citation 

Lipids, vol. 48, no. 1, pp. 87-91

Keywords 

CytotoxicityPetrosiaPetrosiacetylenePolyacetylenic alcoholSponge

Abstract 

A novel petrosiacetylene analog (petrosiacetylene E) has been isolated from the Korean marine sponge Petrosia sp., along with petrosiacetylene A, B and C. Their structures were elucidated on the basis of spectroscopic methods and the stereochemistry of the new compound was determined by using the modified Mosher's method. Petrosiacetylene E showed higher cytotoxicity against five human cancer cell lines than petrosiacetylene A and B, presumably due to the additional hydroxy group located at C-16.

ISSN 

0024-4201

Link 

http://dx.doi.org/10.1007/s11745-012-3727-5

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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