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Title 

Comparative proteomics using lipid over-producing or less-producing mutants unravels lipid metabolisms in Chlamydomonas reinhardtii

Authors 

Y E ChoiH HwangH S KimJ W AhnWon Joong JeongJ W Yang

Publisher 

Elsevier

Issue Date 

2013

Citation 

Bioresource Technology, vol. 145, no. 0, pp. 108-115

Keywords 

Chlamydomonas reinhardtiiComparative proteomicsMicroalgal lipid biosynthesisRandom mutagenesis

Abstract 

In this study, proteomic approach was employed to advance our understanding of genes associated with microalgal lipid production. We first generated random mutants of Chlamydomonas reinhardtii, which displayed increased or decreased lipid content, compared to that in the wild-type. Mutants were designated as CR12 and CR48. Then, the changes of protein expression associated with the mutations of Chlamydomonas reinhardtii were analyzed. We could identify proteins that were significantly up-regulated or down-regulated either in the wild-type or CR12 or CR48. Our results will help understand additional genes or pathways directly or indirectly linked to microalgal lipid production.

ISSN 

0960-8524

Link 

http://dx.doi.org/10.1016/j.biortech.2013.03.142

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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