상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

PTP 1B inhibitory action of a phytochemical propanoic acid, 2-(3-acetoxy-4,4,14-trimethylandrost-8-en-17-yl)

Authors 

M VenkatachalamG SingaraveluK GovindarajuJong Seog Ahn

Publisher 

Indian Academy of Sciences

Issue Date 

2013

Citation 

Current Science, vol. 105, no. 6, pp. 827-831

Keywords 

Cassia auriculataInsulin resistancePropanoic acidProtein tyrosine phosphatase

Abstract 

Bioassay-guided study of the n-butanol fraction of hydromethonolic flower extract of Cassia auriculata, propanoic acid, 2-(3-acetoxy-4,4,14-trimethylandrost- 8-en-17-yl) has demonstrated potential as a protein tyrosine phosphatase 1B (PTP 1B) inhibitor. An in vivo study using Wistar rats has demonstrated that propanoic acid exerted a hypoglycemic action when given orally. The results highlight the green chemistry approach in developing novel PTP 1B inhibitor.

ISSN 

0011-3891

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


Files in This Item: SizeFormat
11846.pdf188KbAdobe PDF
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)