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Title 

Randomized double-blind placebo-controlled trial of powdered Brassica rapa ethanol extract on alteration of body composition and plasma lipid and adipocytokine profiles in overweight subjects

Authors 

S M JeonJ E KimS K ShinE Y KwonU J JungN I BaekK T LeeTae Sook JeongH G ChungM S Choi

Publisher 

Mary Ann Liebert

Issue Date 

2013

Citation 

Journal of Medicinal Food, vol. 16, no. 2, pp. 133-138

Keywords 

body compositionhumanslipids

Abstract 

We evaluated the effects of Brassica rapa ethanol extract (BREE) on body composition and plasma lipid profiles through a randomized, double-blind, and placebo-controlled trial in overweight subjects. Fifty-eight overweight participants (age 20-50 years, body mass index23.0-24.9) were randomly assigned to two groups and served BREE (2 g/day) or placebo (starch, 2 g/day) for 10 weeks. Body compositions, nutrients intake, plasma lipids, adipocytokines, and hepatotoxicity biomarkers were assessed in all subjects at baseline and after 10 weeks of supplementation. The plasma total cholesterol (total-C) concentration was significantly increased after 10 weeks compared to the baseline in both groups. However, BREE supplementation significantly increased the high-density lipoprotein cholesterol (HDL-C) concentration and significantly reduced the total-C/HDL-C ratio, free fatty acid, and adipsin levels after 10 weeks. No significant differences were observed in body compositions, fasting blood glucose, plasma adipocytokines except adipsin, and aspartate aminotransferase and alanine aminotransferase activities between before and after trial within groups as well as between the two groups. The supplementation of BREE partially improves plasma lipid metabolism in overweight subjects without adverse effects.

ISSN 

1096-620X

Link 

http://dx.doi.org/10.1089/jmf.2012.2249

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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