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Title 

A genome-wide resource of cell cycle and cell shape genes of fission yeast

Authors 

J HaylesV WoodL JefferyK L HoeDong Uk KimH O ParkS Salas-PinoC HeichingerP Nurse

Publisher 

The Royal Society

Issue Date 

2013

Citation 

Open Biology, vol. 3, no. 5, pp. 130053-130053

Abstract 

To identify near complete sets of genes required for the cell cycle and cell shape, we have visually screened a genome-wide gene deletion library of 4843 fission yeast deletion mutants (95.7% of total protein encoding genes) for their effects on these processes. A total of 513 genes have been identified as being required for cell cycle progression, 276 of which have not been previously described as cell cycle genes. Deletions of a further 333 genes lead to specific alterations in cell shape and another 524 genes result in generally misshapen cells. Here, we provide the first eukaryotic resource of gene deletions, which describes a near genome-wide set of genes required for the cell cycle and cell shape

ISSN 

2046-2441

Link 

http://dx.doi.org/10.1098/rsob.130053

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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