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Title 

Ginsenoside Rb1 is transformed into Rd and Rh2 by Microbacterium trichothecenolyticum

Authors 

H KimJ H KimPhil Young LeeKwang-Hee BaeS ChoByoung Chul ParkH ShinSung Goo Park

Publisher 

The Korean Society for Applied Microbiology

Issue Date 

2013

Citation 

Journal of Microbiology and Biotechnology, vol. 23, no. 12, pp. 1802-1805

Keywords 

BiotransformationGinsenosideMicrobacteriumTLC

Abstract 

Ginsenosides are the most important ingredient of ginseng and are known to possess many pharmacological and biological effects. Rb1, a major protopanaxadiol ginsenoside, is the most abundant ginsenoside in Panax ginseng C.A Meyer and can be hydrolyzed into more pharmaceutically potent minor ginsenosides. To identify a microorganism that is capable of converting Rb1 into other ginsenosides, we screened 12 Microbacterium spp., and M. trichothecenolyticum was identified as a likely candidate. M. trichothecenolyticum converted Rb1 into Rd and then into Rh2 based on TLC and HPLC analyses of reaction products. This biotransformation method can be easily applied for mass production of Rd and Rh2 by using Rb1.

ISSN 

1017-7825

Link 

http://dx.doi.org/10.4014/jmb.1307.07049

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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