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Title 

Chemical composition, anti-inflammatory activity and cytotoxic activity of the liposoluble constituents from different parts of Acanthopanax evodiaefolius by the Herbal Blitzkrieg Extractor

Authors 

W C HuangZ LiX J LiL M GongX Q LiuOk-Kyoung KwonH X YeHyeong Kyu Lee

Publisher 

Elsevier

Issue Date 

2014

Citation 

Environmental Toxicology and Pharmacology, vol. 38, no. 2, pp. 406-411

Keywords 

Acanthopanax evodiaefoliusAnti-inflammatoryCytotoxic activityHerbal blitzkrieg extractorLiposoluble constituentsNitric oxide

Abstract 

The liposoluble constituents of leaves (LCL) and stem barks (LCSB) from Acanthopanax evodiaefolius Franch were extracted by Herbal Blitzkrieg Extractor (HBE), and their chemical composition was analyzed by GC-MS. 18 compounds were identified, representing 71.98% of LCL, while 35 compounds were identified, accounting for 98.28% of the LCSB. Their cytotoxic activity and inhibitory effect on nitric oxide (NO) production in LPS-stimulated RAW 264.7 cells were tested and the LCL showed significant NO, IL-6 and TNF-α inhibition activity. These results provide the scientific basis for looking for new natural anti-inflammatory substances and exploiting and developing resources of A. evodiaefolius Franch.

ISSN 

1382-6689

Link 

http://dx.doi.org/10.1016/j.etap.2014.07.005

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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