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Title 

Corilagin with inhibitory activity against NO production from Euphorbia supina

Authors 

H S ChaeY M KimE J LeeHyuk-Hwan SongSei-Ryang OhY H ChoiY W Chin

Publisher 

Korean Society of Pharmacognosy

Issue Date 

2014

Citation 

Natural Products Sciences, vol. 20, no. 2, pp. 126-129

Keywords 

CorilaginEuphorbia supinaEuphorbiaceaeNitric oxideTannin

Abstract 

Bioactivity-guided investigation on whole plant of Euphorbia supina, using LPS-induced Raw264.7 cells, led to the identificaiton of a tannin which was not reported from this plant along with four known constituents (quercetin, astragalin, juglanin and methyl gallate). The structure of the tannin was determined as corilagin by the interpretation of NMR (1D and 2D) and MS spectroscopic data. All the isolates were tested for the inhibitory activity against NO production in LPS-induced Raw264.7 cells. Among the tested isolates, corilagin was found to be the most active compound

ISSN 

1226-3907

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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