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Title 

Inhibition of diacylglycerol acyltransferase by prenylated flavonoids isolated from the stem bark of Maackia amurensis

Authors 

N LiN ZhangJ L LiP G DuHyun Sun LeeL Cui

Publisher 

Taylor & Francis

Issue Date 

2015

Citation 

Journal of Asian Natural Products Research, vol. 17, no. 2, pp. 178-181

Keywords 

DGATLeguminosaeMaackia amurensisprenylated flavanone

Abstract 

A new prenylated flavanone, erythraddison Z (1), together with eight known flavonoids (2-9), was isolated from the stem bark of Maackia amurensis. Their structures were elucidated on the basis of spectroscopic methods, including 1D and 2D NMR (COSY, HMQC, and HMBC) techniques. All the isolates, with the exception of 3, 6 and 7, strongly inhibited diacylglycerol acyltransferase activity in an in vitro assay with IC50 values ranging from 96.5 ± 0.6 to 135.1 ± 1.4 M.

ISSN 

1028-6020

Link 

http://dx.doi.org/10.1080/10286020.2014.960402

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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