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Title 

Genome-wide identification and classification of microRNAs derived from repetitive elements

Authors 

J A GimH S HaK AhnDae Soo KimH S Kim

Publisher 

Korea Genome Organization

Issue Date 

2014

Citation 

Genomics & Informatics, vol. 12, no. 4, pp. 261-267

Keywords 

interspersed repetitive sequencesmicroRNAnovel miRNAspalindromic structure

Abstract 

MicroRNAs (miRNAs) are known for their role in mRNA silencing via interference pathways. Repetitive elements (REs) share several characteristics with endogenous precursor miRNAs. In this study, 406 previously identified and 1,494 novel RE-derived miRNAs were sorted from the GENCODE v.19 database using the RepeatMasker program. They were divided into six major types, based on their genomic structure. More novel RE-derived miRNAs were confirmed than identified as RE-derived miRNAs. In conclusion, many miRNAs have not yet been identified, most of which are derived from REs.

ISSN 

1598-866X

Link 

http://dx.doi.org/10.5808/GI.2014.12.4.261

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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