상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

Cosmetic activities of nyasol from the rhizomes of Anemarrhena asphodeloide

 

지모의 뿌리줄기로부터 분리된 nyasol의 미용효과

Authors 

Yhun Jung ParkC S KuM J KimM K LeeKi Ohk KimHyung Won RyuHyuk-Hwan SongDoo-Young KimSei-Ryang Oh

Publisher 

Korean Society of Applied Biological Chemistry

Issue Date 

2015

Citation 

Journal of Applied Biological Chemistry, vol. 58, no. 1, pp. 31-38

Keywords 

Anemarrhena asphodeloideAnti-atopyAnti-whiteningNitric oxideNyaso

Abstract 

The rhizomes of Anemarrhena asphodeloide was extracted with 100% ethanol and concentrated subfractions were separated with medium pressure liquid chromatography-based activity profiling. One compound was isolated from the subfraction 10 through the repeated preparative high performance liquid chromatography (prep-HPLC). According to physico-chemical and spectroscopic data including NMR and MS, the chemical structures of the compound was determined as nyasol (1). Nyasol was exhibited potent inhibitory activity for NO (IC50: 12.5 ?g/mL), tyrosinase (IC50: 12.5 ?g/mL), melanin contents (IC50: 12.5 ?g/mL), thymus and activation-regulated chemokine (TARC) production (IC50: 6.25 ?g/mL). As a result, nyasol has an excellent inflammation-dependent anti-whitening and TARC production activity. It could be used to a large range of functional cosmetics.

ISSN 

1229-2737

Link 

http://dx.doi.org/10.3839/jabc.2015.007

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)