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Title 

Nanomaterials for enhanced immunity as an innovative paradigm in nanomedicine

Authors 

A SethDoo-Byoung OhY T Lim

Publisher 

Future Medicine

Issue Date 

2015

Citation 

Nanomedicine, vol. 10, no. 6, pp. 959-975

Keywords 

adjuvantantigenantigen presenting cellscross-presentationimmune responsenanoparticlevaccine

Abstract 

Since the advent of nanoparticle technology, novel and versatile properties of nanomaterials have been introduced, which has constantly expanded their applications in therapeutics. Introduction of nanomaterials for immunomodulation has opened up new avenues with tremendous potential. Interesting properties of nanoparticles, such as adjuvanticity, capability to enhance cross-presentation, polyvalent presentation, siRNA delivery for silencing of immunesuppressive gene, targeting and imaging of immune cells have been known to have immense utility in vaccination and immunotherapy. A thorough understanding of the merits associated with nanomaterials is crucial for designing of modular and versatile nanovaccines, for improved immune response. With the emerging prerequisites of vaccination, nanomaterial-based immune stimulation, seems to be capable of taking the field of immunization to a next higher level.

ISSN 

1743-5889

Link 

http://dx.doi.org/10.2217/nnm.14.200

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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