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Title 

Surface plasmon resonance: a versatile technique for biosensor applications

Authors 

H H NguyenJeho ParkS KangMoonil Kim

Publisher 

MDPI AG

Issue Date 

2015

Citation 

Sensors, vol. 15, no. 5, pp. 10481-10510

Keywords 

ApplicationsBiosensorSPRSPR imagingSurface plasmon resonance

Abstract 

Surface plasmon resonance (SPR) is a label-free detection method which has emerged during the last two decades as a suitable and reliable platform in clinical analysis for biomolecular interactions. The technique makes it possible to measure interactions in real-time with high sensitivity and without the need of labels. This review article discusses a wide range of applications in optical-based sensors using either surface plasmon resonance (SPR) or surface plasmon resonance imaging (SPRI). Here we summarize the principles, provide examples, and illustrate the utility of SPR and SPRI through example applications from the biomedical, proteomics, genomics and bioengineering fields. In addition, SPR signal amplification strategies and surface functionalization are covered in the review.

ISSN 

1424-8220

Link 

http://dx.doi.org/10.3390/s150510481

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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