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Title 

Suvanine analogs from a Coscinoderma sp. marine sponge and their cytotoxicities against human cancer cell lines

Authors 

J W LeeH S LeeJ ShinJong Soon KangJieun YunH J ShinJ S LeeY J Lee

Publisher 

Pharmaceutical Society of Korea

Issue Date 

2015

Citation 

Archives of Pharmacal Research, vol. 38, no. 6, pp. 1005-1010

Keywords 

CoscinodermaCytotoxicityHuman cancer cell lineMarine spongeSulfated sesterterpenoidSuvanine

Abstract 

Nine suvanine analogs including suvanine phenethylammonium salt and two new compounds were isolated from the marine sponge Coscinoderma sp., collected from Chuuk State, Federated States of Micronesia. The structures of the new compounds were elucidated by 2D NMR and HRMS analyses. Suvanine and a new analog exhibited weak but selective cytotoxicity against colon (HCT-15), lung (NCI-H23), stomach (NUGC-3), and prostate (PC-3) cancer cell lines.

ISSN 

0253-6269

Link 

http://dx.doi.org/10.1007/s12272-014-0479-1

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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