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Title 

Chemical constituents from Belamcanda chinensis and their inhibitory effects on nitric oxide production in RAW 264.7 macrophage cells

Authors 

J W LeeChul LeeQ JinM S LeeY KimJ T HongM K LeeB Y Hwang

Publisher 

Pharmaceutical Society of Korea

Issue Date 

2015

Citation 

Archives of Pharmacal Research, vol. 38, no. 6, pp. 991-997

Keywords 

Belamcanda chinensisFlavonoidIridaceaeNitric oxide inhibitor

Abstract 

Belamcanda chinensis (L.) DC., which belongs to the family of Iridaceae, has been used as a folk medicine for the treatment of inflammation, asthma, tonsillitis, and many other throat disorders. Bioactivity-guided purification of the methylene chloride-soluble fraction of the rhizomes of B. chinensis based on the inhibition of nitric oxide production led to the identification of seventeen known compounds. Their structures were elucidated on the basis of extensive spectroscopic measurement such as NMR and ESI-MS. All of the isolated compounds were evaluated for their inhibitory effects on nitric oxide production in LPS-induced RAW 264.7 macrophage cells.

ISSN 

0253-6269

Link 

http://dx.doi.org/10.1007/s12272-014-0529-8

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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