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Title 

Haenamindole, an unusual diketopiperazine derivative from a marine-derived Penicillium sp. KCB12F005

 

해양유래사상균 Penicillium sp. KCB12F005로부터 분리한 신규 해남인돌

Authors 

Jong Won KimSung-Kyun KoSangkeun SonKee Sun ShinIn Ja RyooYoung-Soo HongH OhB Y HwangH HirotaS TakahashiBo Yeon KimH OsadaJae-Hyuk JangJong Seog Ahn

Publisher 

Elsevier

Issue Date 

2015

Citation 

Bioorganic & Medicinal Chemistry Letters, vol. 25, no. 22, pp. 5398-5401

Keywords 

Diketopiperazine alkaloidMarine-derived fungusPenicillium sp.Pyrimidoindoleβ-Phenylalanine

Abstract 

During the chemical investigation of marine-derived fungus, an unusual diketopiperazine (DKP) alkaloid, haenamindole (1), was isolated from a culture of the marine-derived fungus Penicillium sp. KCB12F005. The structure of 1, which possesses benzyl-hydroxypiperazindione and phenyl-pyrimidoindole rings system in the molecule, was elucidated by analysis of NMR and MS data. The stereochemistry of 1 was determined by ROESY and advanced Marfey's method.

ISSN 

0960-894X

Link 

http://dx.doi.org/10.1016/j.bmcl.2015.09.026

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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