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Title 

Lanostane triterpenes isolated from Antrodia heteromorpha and their inhibitory effects on RANKL-induced osteoclastogenesis

Authors 

J KwonH LeeYeo Dae YoonB Y HwangY GuoJong Soon KangJ J KimD Lee

Publisher 

American Chemical Society

Issue Date 

2016

Citation 

Journal of Natural Products, vol. 79, no. 6, pp. 1689-1693

Abstract 

Two new spiro-lanostane triterpenoids, antrolactones A and B (1 and 2), along with polyporenic acid C (3), were isolated from an EtOAc-soluble extract of Antrodia heteromorpha culture medium, and the chemical structures of the new compounds were elucidated by application of NMR, MS, and ECD spectroscopic techniques. All isolated compounds exhibited inhibitory effects on receptor activator of nuclear factor-kappaB ligand-induced osteoclastogenesis.

ISSN 

0163-3864

Link 

http://dx.doi.org/10.1021/acs.jnatprod.6b00207Document

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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