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Title 

Identification of mycobacterial antigens in human urine by use of immunoglobulin g isolated from sera of patients with active pulmonary tuberculosis

Authors 

Sun Hee KimNan Ee LeeJ S LeeJ H ShinJ Y LeeJeong Heon KoC L ChangYong Sam Kim

Publisher 

American Society for Microbiology

Issue Date 

2016

Citation 

Journal of Clinical Microbiology, vol. 54, no. 6, pp. 1631-1637

Abstract 

Point-of-care (POC) diagnostic testing of tuberculosis (TB) is a tremendous unmet need. In this study, four urinary mycobacterial antigens were identified through two independent approaches using IgG capture and immunodepletion methods. Among these, ModC was validated by a multiple reaction monitoring (MRM) method. As expected, the biomarkers elevated the clinical validity of TB diagnosis when combined with preexisting markers.

ISSN 

0095-1137

Link 

http://dx.doi.org/10.1128/JCM.00236-16

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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