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Title 

New chromene derivatives with radical scavenging activities from the brown alga Sargassum siliquastrum

Authors 

H S KangJong-Pyung Kim

Publisher 

Science Reviews 2000

Issue Date 

2017

Citation 

Journal of Chemical Research

Keywords 

Brown algaChromeneNatural productsRadical scavengers

Abstract 

The organic extract of Sargassum siliquastrum exhibited in vitro radical scavenging activity in our screening of marine brown algae collected in Jeju Island, Korea. Bioactivity-guided fractionation of the organic extract led to the isolation of two new meroterpenoids, named sargachromanols S and T, along with the known meroterpenoids, isopolycerasoidol, nahocol D2, and sargachromanols D, E, G, and I. The planar structures of the new compounds were determined by the analysis of spectroscopic data obtained by HREIMS and 1D and 2D NMR. The structures of the new compounds sargachromanols S and T were closely related to those of previously isolated sargachromanols D and A, respectively. The isolated compounds showed radical scavenging activities in vitro against 1,1-diphenylpicrylhydrazyl and 2,2′-azidobis(3-ethylbenzothiazoline-6-sulfonate) radicals.

ISSN 

1747-5198

Link 

http://dx.doi.org/10.3184/174751917X14859570937631

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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