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Title 

Advanced carbon dots via plasma-induced surface functionalization for fluorescent and bio-medical applications

Authors 

S Y ParkC Y LeeH R AnH KimY C LeeE C ParkH S ChunH Y YangSae Hae ChoiHee-Sik KimK S KangH G ParkJ P KimY ChoiJ LeeH U Lee

Publisher 

Royal Society of Chemistry

Issue Date 

2017

Citation 

Nanoscale

Abstract 

Multifunctional carbon-based nanodots (C-dots) are synthesized using atmospheric plasma treatments involving reactive gases (oxygen and nitrogen). Surface design was achieved through one-step plasma treatment of C-dots (AC-paints) from polyethylene glycol used as a precursor. These AC-paints show high fluorescence, low cytotoxicity and excellent cellular imaging capability. They exhibit bright fluorescence with a quantum yield twice of traditional C-dots. The cytotoxicity of AC-paints was tested on BEAS2B, THLE2, A549 and hep3B cell lines. The in vivo experiments further demonstrated the biocompatibility of AC-paints using zebrafish as a model, and imaging tests demonstrated that the AC-paints can be used as bio-labels (at a concentration of <5 mg mL-1). Particularly, the oxygen plasma-treated AC-paints (AC-paints-O) show antibacterial effects due to increased levels of reactive oxygen species (ROS) in AC-paints (at a concentration of >1 mg mL-1). AC-paints can effectively inhibit the growth of Escherichia coli (E. coli) and Acinetobacter baumannii (A. baumannii). Such remarkable performance of the AC-paints has important applications in the biomedical field and environmental systems

ISSN 

2040-3364

Link 

http://dx.doi.org/10.1039/c7nr03026f

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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