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Title 

Antifungal activities of dimeric sesquiterpenes, shizukaols C and F, isolated from Chloranthus japonicus sieb

Authors 

Tae-Hoon KangY M LeeWon Jung LeeE I HwangK D ParkG J ChoiJae Sun MoonHo Yong ParkSung Uk Kim

Publisher 

The Korean Society for Applied Microbiology

Issue Date 

2017

Citation 

Journal of Microbiology and Biotechnology

Keywords 

Antifungal activityChloranthus japonicus SiebPhytophthora infestansPuccinia reconditeShizukaol CShizukaol F

Abstract 

Two dimeric sesquiterpenes were separated from Chloranthus japonicus Sieb. and identified as shizukaols C and F. They exhibited potent antifungal activities (MICs = 4-16 μg/ml) in vitro against various plant pathogenic fungi (Pythium ultimum, Phytophthora infestans, Botrytis cinerea, Colletotrichum lagenarium, Alternaria kikuchiana, and Magnaporthe grisea). Shizukaol C showed 88% and 91% protective activities in the greenhouse against Puccinia recondita (wheat leaf rust) and Phytophthora infestans (tomato late blight), respectively, at 100 μg/ml; shizukaol F exhibited 93% antifungal activity against Puccinia recondita at the same concentration. Therefore, these compounds might serve as interesting candidates for effective antifungal agents.

ISSN 

1017-7825

Link 

http://dx.doi.org/10.4014/jmb.1612.12051

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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