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Title 

Anti-inflammatory effect of lactic acid bacteria isolated from kimchi on acid-induced acute colitis in model mice

Authors 

S Y LeeS S SekhonHyung Cheol KimK WonJ Y AhnK LeeY H Kim

Publisher 

Springer Verlag (Germany)

Issue Date 

2017

Citation 

Toxicology and Environmental Health Sciences

Keywords 

Anti-inflammationColitisLactic acid bacteriaOral supplementation

Abstract 

Lactic acid bacteria (LAB) provide numerous beneficial effects on the host body, especially on the intestine. Two LAB strains isolated from Kimchi, Leuconostoc mesenteroides and Lactobacillus sakei, were studied for its anti-inflammatory activity in acidinduced acute colitis in mice. To induce acute colitis in model mice (C57BL/6), 3% of dextran sulfate sodium treatment was treated for 7 days. Assessment of necropsy and histopathology analysis showed that oral supplementation of both L. mesenteroides and L. sakei ameliorated the symptoms of acute colitis. Moreover, the mixture of L. meseneroides and L. sakei showed synergistic effect on colitis. The results suggest that the formulation of L. mesenteroides and L. sakei mixture could be used as an oral supplementation to decrease the inflammatory harmful environment associated with colitis

ISSN 

2005-9752

Link 

http://dx.doi.org/10.1007/s13530-017-0332-2

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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