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Title 

Coating of an antimicrobial peptide on solid substrate via initiated chemical vapor deposition

Authors 

G M JeongH SeongS G ImBong Hyun SungS C KimK J Jeong

Publisher 

Elsevier

Issue Date 

2018

Citation 

Journal of Industrial and Engineering Chemistry

Keywords 

Antimicrobial peptideCoatingiCVDLatex glove

Abstract 

We developed a simple and efficient method for the immobilization of a potent AMP (SHAP1) on the surface of solid supports via initiated chemical vapor deposition (iCVD). The surface of the slide glass was functionalized with vinyl-containing polymer by iCVD, and Cys-linked SHAP1 peptides could be immobilized on the functionalized surface (glass and latex glove) via simple thiol-ene click chemistry with high efficiency. The antimicrobial efficacy of the immobilized peptides was investigated against two typical pathogenic bacteria ― Escherichia coli and Staphylococcus aureus ― and it was revealed that SHAP1-GS-Cys exhibited high antibacterial efficacy (>96%).

ISSN 

1226-086X

Link 

http://dx.doi.org/10.1016/j.jiec.2017.09.006

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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