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Title 

Genetic incorporation of l-dihydroxyphenylalanine (DOPA) biosynthesized by a tyrosine phenol-lyase

Authors 

S KimBong Hyun SungS C KimH S Lee

Publisher 

Royal Society of Chemistry

Issue Date 

2018

Citation 

Chemical Communications

Abstract 

l-Dihydroxyphenylalanine (DOPA) was biosynthesized by a tyrosine-phenol lyase from catechol, pyruvate, and ammonia in Escherichia coli, and the biosynthesized amino acid was directly incorporated into proteins. Three biochemical experiments with mutant proteins containing DOPA confirmed the genetic incorporation of biosynthesized DOPA, and revealed its potential for various biochemical applications

ISSN 

1359-7345

Link 

http://dx.doi.org/10.1039/c8cc00281a

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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