상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

Four new flavonoids with DGAT inhibitory activity from Psoralea corylifolia

Authors 

H Z LiX MengY Y JiangX LinD X XiongD WangHyun Sun LeeL Cui

Publisher 

Elsevier

Issue Date 

2018

Citation 

Phytochemistry Letters

Keywords 

DGATObesityPsoralea corylifolia

Abstract 

Four new compounds, 3′'-methoxy-bavacoumestan C (1), 6,7-furanbavachinone B (2), 3,4- furanbavachalcone A (3) and 4,5- furanbavachalcone A (4), together with seven known flavonoids were isolated from the Psoralea corylifolia. Their structures were determined by extensive spectroscopic and physicochemical analyses. All the compounds (1?11) were evaluated for in vitro inhibitory activity against DGAT. Among them, compounds 1, 6, 7, 10 and 11 were found to exhibit selective inhibitory activity on DGAT1with IC50 values ranging from 78.5 ± 1.7 to 153.4 ± 1.5 μM.

ISSN 

1874-3900

Link 

http://dx.doi.org/10.1016/j.phytol.2018.10.005

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)