상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

Genomic organization of purK and purE in Brevibacterium ammoniagenes ATCC 6872 : purE locus provides a clue for genomic evolution

Authors 

Sung-Oh ChungJin-Ho LeeSe Yong LeeDae Sil Lee

Publisher 

Wiley-Blackwell

Issue Date 

1996

Citation 

FEMS Microbiology Letters, vol. 137, no. 2, pp. 265-268

Keywords 

brevibacterium ammoniagenesgenomic organizationpurepurkbrevibacteriumdna sequenceevolutiongene locusgenetic analysisgenetic organization

Abstract 

From the genomic library of Brevibacterium ammoniagenes ATCC6872, the pitrE locus encoding 5′-phosphoribosyl-5-aminoimidazole (AIR) carboxylase (EC 4.1.1.21) was cloned and its nucleotide sequence was determined. From the sequence analysis, two distinct open reading frames (ORFs) in the sequence of the purE locus were identified as purK and purE genes (purK-purE). An in vivo translation experiment reconfirmed the purK and purE genes to be independent. The genomic organization in the purE locus of B. ammoniagenes is opposite to that of the bacteria Escherichia coli and Bacillus subtilis. However, it coincides with the fused genes (purKE) of higher organisms Sacckaromyces cerevisiae, Schizosaccharomyces pombe and Vigna aconitifolia. This suggests that the purE locus might be an intermediate form for genomic evolution of bacteria to higher organisms.

ISSN 

0378-1097

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)