상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

Cloning and characterization of cDNAs coding for heavy and light chains of a monoclonal antibody(MabB23) specific for human plasma apolipoprotein B-100

Authors 

Ju Won KwakByung-Kwon ChoiDong-Ik LeeTong-Koo KangYoung-Gyo SeoWon-Kyung ChoMoon Hi Han

Publisher 

Elsevier

Issue Date 

1996

Citation 

Gene, vol. 169, no. 2, pp. 237-239

Keywords 

Apo B-100cholesterolFabhyperlipidaemiaimmunoglobulinlow-density lipoproteinspolymerase chain reactionrecombinant DNAapolipoprotein b100complementary dna

Abstract 

We have determined the nucleotide sequences encoding the heavy and light chains of the Fab fragment of murine monoclonal antibody MabB23 (γ2b,λ), which is specific for human plasma apolipoprotein B-100 of low-density lipoproteins. The sequence analyses revealed that the variable regions of the heavy and light chains are members of mouse heavy-chain subgroup I(B) and λ light-chain, respectively. A few unusual amino acids in the framework and constant regions of the heavy-chain were also noticed.

ISSN 

0378-1119

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)