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Title 

Structure determination and biological activities of elaiophylin produced by Streptomyces sp. MCY-846

Authors 

S Y LeeMi Soon KimHang Sub KimYoung Ho KimS D HongJung Joon Lee

Publisher 

The Korean Society for Applied Microbiology

Issue Date 

1996

Citation 

Journal of Microbiology and Biotechnology, vol. 6, no. 4, pp. 245-249

Keywords 

antibacterial activitycytotoxicityelaiophylinnitric oxide

Abstract 

A cytotoxic compound, 846I was isolated from the culture of Streptomyces sp. strain MCY846 by its cytotoxicity against gastric cancer cell line SNU-1. The IR, UV and NMR spectra of 846I were identical to those of elaiophylin. This compound showed moderate cytotoxicity against several cell lines and exerted strong inhibitory effect on the synthesis of nitric oxide in the lipopolysaccharide stimulated-Raw 264.7 cells.

ISSN 

1017-7825

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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