상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

In vitro anticomplementary activity of phenylpropanoids from Agastache rugosa

Authors 

Sei Ryang OhKeun Young JungHyeong Kyu Lee

Publisher 

Korean Society of Pharmacognosy

Issue Date 

1996

Citation 

Korean Journal of Pharmacognosy, vol. 27, no. 1, pp. 20-25

Keywords 

agastache rugosaanticomplement activitycaffeic acid methyl esterrosmarinic acidrosmarinic acid methyl ester

Abstract 

In searching for anticomplementary compounds, three phenylpropanoids were isolated from the roots of Agastache rugosa and identified as rosmarinic acid (RA), rosmarinic acid methyl ester (RAM) and caffeic acid methyl ester (CAM) by NMR analyses. RA and RAM exhibited strong inhibitory activity on both the classical pathway (CP) and the alternative pathway (AP) of the complement system, in vitro, but CAM did far less than RA and RAM. RAM-MI~-M5, the methylated derivatives from the RAM, showed that the inhibitory activity was decreased in inverse proportion to the number of methylated groups and RAM-M 2~-M4, the isomers of two methylated hydroxyl groups, exhibited different inhibition activity.

ISSN 

0253-3073

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)