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Title 

The use of inulinase pre-pro leader peptide for secretion of heterologous proteins in Saccharomyces cerevisiae

Authors 

Bong Hyun ChungByung Moon KimSoo Wan Nam

Publisher 

Springer Verlag (Germany)

Issue Date 

1996

Citation 

Biotechnology Letters, vol. 18, no. 6, pp. 627-632

Keywords 

inulinaseproteinsignal peptideprotein secretionsaccharomyces cerevisiae

Abstract 

The pre-pro and pre regions of inulinase leader peptide have been used to secrete the heterologous proteins such as human lipocortin-l and human interleukin-2 (IL2) in Saccharomyces cerevisiae. The inulinase leader peptide consisting of both pre and pro regions directed an efficient secretion of such heterologous proteins in S. cerevisiae, while deletion of pro region prevents them from being secreted. Both pre and pro regions of inulinase leader peptide appears to be necessary to direct secretion of heterologous proteins in S. cerevisiae.

ISSN 

0141-5492

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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