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Title 

Improvement of hydroxyvalerate fraction in poly(β-hydroxybutyrate-co-β-hydroxyvalerate) by a mutant strain of Alcaligenes eutrophus

Authors 

In Young LeeGuk Jin KimDae Keon KimBo Kyoung YeonYoung Hoon Park

Issue Date 

1996

Citation 

Journal of Fermentation and Bioengineering, vol. 81, no. 3, pp. 255-258

Keywords 

hydroxyvaleratemutantP(HB-co-HV)3 hydroxybutyric acidbacterial metabolismbacterium mutantfermentationnonhumanstrain differencewautersia eutropha

Abstract 

In an effort to improve the strain activity of Alcaligenes eutrophus to produce poly(β-hydroxybutyrate-coβ-hydroxyvalerate) [P(HB-co-HV)], a mutant strain BK23 was obtained by MNNG mutagenesis. With the strain, the fraction of hydroxyvalerate (HV) and its yield from propionic acid were found to be significantly unproved compared to those of the parent strain, A. eutrophus NCIMB 11599. In a fed-batch culture, the mutant strain produced 47 g/l of P(HB-co-HV) with an HV fraction of 22 mol%, while the parent strain could yield only the much lower fraction of 10 mol%.

ISSN 

0385-6380

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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