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Title 

Immunostimulating components from the root of Angelica gigas Nakai

 

참당귀(Angelica gigas Nakai) 뿌리의 면역증강활성 성분

Authors 

Kyung Seop AhnWoong Seop SimHwan Mook KimSang Bae HanIk Hwan Kim

Publisher 

Korean Society of Pharmacognosy

Issue Date 

1996

Citation 

Korean Journal of Pharmacognosy, vol. 27, no. 3, pp. 254-261

Keywords 

Angelica gigasarabinogalactanimmuno-stimulating activitymixed leukocyte reactionpectic polysaccharideangelica gigas extractimmunostimulating agent

Abstract 

A potent immune-stimulating activity was detected from the watersoluble and ethanol-precipitated crude extract (AG-1) of the root of Angelica gigas Nakai. The crude extract was fractionated into two fractions, an acidic AG-2 and a neutral AG-3 fraction by DEAE-cellulose adsorption. The two fractions contained polysaccharides of which M.W. were 10 Kdal and >2,000 Kdal respectively, proteins, and vanous inorganic components. The immunostimulating activities of two fractions were not reduced by proteinase K, acid or alkali treatment. The polysaccharides obtained from the root of A. gigas were mainly composed of arabinose, galactose, and galacturonic acid. These results indicated that immune-stimulating components of the root of A. gigas was a kind of pectic polysaccharides or arabinogalactans.

ISSN 

0253-3073

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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