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Title 

New indole derivatives with free radical scavenging activity from Agrocybe cylindracea

Authors 

Won Gon KimIn Kyoung LeeJong Pyung KimIn Ja RyooH KoshinoIck Dong Yoo

Publisher 

American Chemical Society

Issue Date 

1997

Citation 

Journal of Natural Products, vol. 60, no. 7, pp. 721-723

Keywords 

6 hydroxy 1h indole 3 acetamide6 hydroxy 1h indole 3 carboxaldehydefree radicalindole derivativeFree Radical ScavengersIndolesAgrocybe cylindracea

Abstract 

Two new indole derivatives were isolated as free radical scavengers from the MeOH extract of Agrocybe cylindracea. The structures of these compounds were determined to be 6-hydroxy-1H-indole-3-carboxaldehyde (1) and 6-hydroxy- 1H-indole-3-acetamide (2) on the basis of spectroscopic studies. Compounds 1 and 2 inhibited lipid peroxidation in rat liver microsomes, with IC50 values of 4.1 and 3.9 μg/mL, respectively.

ISSN 

0163-3864

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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