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Title 

Cloning and characterization of cDNAs coding for heavy and light chains of a monoclonal antibody specific for the S antigen of hepatitis B virus

Authors 

Chun Jeih RyuByung Rae JinHong Keung ChungMoon Hi HanHyo Jeong Hong

Publisher 

Elsevier

Issue Date 

1994

Citation 

Gene, vol. 144, no. 0, pp. 313-314

Keywords 

HBVimmunoglobulinmousepolymerase chain reactionRecombinant DNAcomplementary dnaimmunoglobulin gimmunoglobulin heavy chainimmunoglobulin light chainrecombinant dna

Abstract 

The nucleotide (nt) sequences encoding the variable regions of the heavy and light chains of a murine monoclonal antibody (mAb) have been determined. The mAb recognizes a disulfide-bond-dependent conformational epitope on the hepatitis B virus surface antigen. The sequence analyses revealed that the variable regions of the heavy and light chains are members of mouse heavy- chain subgroup II(A) and κ light-chain subgroup III, respectively.

ISSN 

0378-1119

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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