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Title 

CETP inhibitory activity of ceramides, isolated from the gorgonian Acabaria undulata

Authors 

Tae Sook JeongJung Ah AhnYoung Kook KimSong Hae BokByoung-Mog KwonJongheon ShinYoungwan Seo

Publisher 

Elsevier

Issue Date 

1997

Citation 

Bioorganic & Medicinal Chemistry Letters, vol. 7, no. 11, pp. 1481-1482

Keywords 

drug activity

Abstract 

Four ceramides, isolated from the gorgonian Acabaria Undulata, and sphingosine analogs exhibited significant cholesteryl ester transfer protein (CETP)-inhibitory activity. The ceramides 1, 2, 3, 4 and N,N-dimethylsphingosine inhibited human CETP with IC50 values of 46.8, 57.3, 86.3, 65.6 and 6.3 μM, respectively.

ISSN 

0960-894X

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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