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Title 

Production of elaiophylin by the strain MCY-846 in a submerged culture

Authors 

Sang Young LeeSang Chul HaYoung Soo HongSoon-Duck HongJung Joon Lee

Publisher 

The Korean Society for Applied Microbiology

Issue Date 

1997

Citation 

Journal of Microbiology and Biotechnology, vol. 7, no. 4, pp. 278-281

Keywords 

Culture conditionElaiophylinIdentification

Abstract 

Streptomyces sp. MCY-846 selected by in vitro cytotoxicity assay produced elaiophylin. Individual characteristics of the strains such as spore morphology, and physiological characteristics indicated that the strain is resembled to Streptomyces hygroscopicus. The time course of cell growth and antibiotic production was observed in the medium containing 0.5% trehalose and 0.5% soybean meal as carbon and nitrogen sources, respectively. The optimum production of elaiophylin was tested with different combinations of carbon and nitrogen sources and reached a maxima of 470 μg/ml in the PC-II medium.

ISSN 

1017-7825

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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