상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

Characterization of doxorubicin-nonproducing mutant, Nu3 of Streptomyces peucetius ATCC27952

Authors 

Cheol Kyu HwangHong-Sub LeeYoung Soo HongNam-Soo PaekTae-Han KimJung Joon Lee

Publisher 

The Korean Society for Applied Microbiology

Issue Date 

1997

Citation 

Journal of Microbiology and Biotechnology, vol. 7, no. 5, pp. 363-366

Keywords 

BioconversionMutantStreptomyces peucetius

Abstract 

A doxorubicin-nonproducing mutant, Nu23 was selected from the mutagenesis of Streptomyces peucetius ATCC27952. Chemical and molecular biological analysis suggested that the mutant was blocked at the step between polyketide synthase and aklaviketon reductase in the biosynthesis of doxorubicin. Furthermore, the bioconversion experiment with the mutant revealed that 13-dihydrodaunorubicin is likely to be a biosynthetic intermediate.

ISSN 

1017-7825

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)