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Title 

Anticomplementary activity of ergosterol peroxide from Naematoloma fasciculare and reassignment of NMR data

Authors 

Dong Seon KimNam-In PaekSei Ryang OhKeun Young JungIm Seon LeeJung Hee KimHyeong Kyu Lee

Publisher 

Pharmaceutical Society of Korea

Issue Date 

1997

Citation 

Archives of Pharmacal Research, vol. 20, no. 3, pp. 201-205

Keywords 

Naematoloma fasciculareAnticomplementary activityErgosterolErgosterol peroxide13C NMR1H NMRHMBC

Abstract 

A very high content (at least 0.23%) of ergosterol peroxide was isolated from Naematoloma fasciculare Karst. Not only ergosterol peroxide but also ergosterol showed very strong anticomplementary activity on the classical pathway, the IC50 values being 5.0 μM and 1.0 μM, respectively. The 1H and 13C NMR data of ergosterol peroxide were revised and completely assigned by DEPT, 1H-1H COSY, HMQC and HMBC correlations.

ISSN 

0253-6269

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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