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Title 

Enhanced synthesis of trisporic acid and β-carotene production in Blakeslea trispora by addition of a non-ionic surfactant, Span 20

Authors 

Seon Won KimWeon Taek SeoYoung Hoon Park

Issue Date 

1997

Citation 

Journal of Fermentation and Bioengineering, vol. 84, no. 4, pp. 330-332

Keywords 

Blakeslea trisporaβ-carotenetrisporic acidSpan 20

Abstract 

When a non-ionic surfactant, Span 20, was added to a mated culture of Blakeslea trispora, β-carotene production increased 15 fold compared to that without the surfactant, reaching 2.3 g/l. The marked increase of β-carotene was closely related to the titer of trisporic acid, a strong stimulator of β-carotene synthesis. With Span 20, the microorganism produced 15 times more trisporic acid (8.8 mg/g dry cell weight) than without the surfactant (0.6 mg/g dry cell weight). Therefore, it was concluded that Span 20 considerably enhanced the production of trisporic acid, which subsequently stimulated β- carotene synthesis.

ISSN 

0385-6380

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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