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Title 

Platelet activating factor antagonist activity of ginsenosides

Authors 

Keun Young JungDong Seon KimSei Ryang OhIm Seon LeeJung Joon LeeJong Dae ParkShin Il KimHyeong Kyu Lee

Publisher 

Pharmaceutical Society of Japan

Issue Date 

1998

Citation 

Biological & Pharmaceutical Bulletin, vol. 21, no. 1, pp. 79-80

Keywords 

Panax ginsengPAF antagonistic activity20(S)-ginsenoside Rg3* D20- ginsenosides Rg3Δ20-ginsenoside Rg

Abstract 

Ginseng saponins and their degradation products have been screened for antagonist activity towards [3H]PAF (platelet activating factor) in washed rabbit platelet receptor binding studies. 20(S)- and Δ20-ginsenosides Rg3, protopanaxadiol-type saponins, were found to be relatively potent PAF antagonists (IC50=4.9 x 10-5 M and 9.2 x 10-5 M, respectively).

ISSN 

0918-6158

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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