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Title 

Platelet-activating factor antagonistic activity and 13C NMR assignment of pregomisin and chamigrenal from Schisandra chinensis

Authors 

Im Seon LeeKeun Young JungSei Ryang OhDong Seon KimJung Hee KimJung Joon LeeHyeong Kyu LeeSeung Ho LeeEun Hee KimChaejoon Cheong

Publisher 

Pharmaceutical Society of Korea

Issue Date 

1997

Citation 

Archives of Pharmacal Research, vol. 20, no. 5, pp. 633-636

Keywords 

Schisandra chinensis BaillSchisandraceaePAF receptor antagonistpregomisinchamigrenal13C NMR

Abstract 

In the course of searching for PAF receptor antagonists, pregomisin (1) and chamigrenal (2) were isolated from the fruits of Schizandra chinensis Baill by the bioactivity-guided isolation. Both compounds showed PAF antagonistic activity and the IC50 values were 4.8×10-5 M and 1.2×10-4 M, respectively. In addition, the 13C NMR assignments of 1 and 2 using DEPT, HMQC, COLOC and HMBC were reported for the first time.

ISSN 

0253-6269

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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