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Title 

Genetic analysis of Borrelia burgdorferi sensu lato in Korea using genomic hybridization and 16S rRNA gene sequence determination

Authors 

Sun Ho KeeJung Hoon YoonHee Bok OhYong Ha ParkYoon Won KimMin Kee ChoKyung Seok ParkWoo Hyun Chang

Publisher 

Wiley-Blackwell

Issue Date 

1996

Citation 

Microbiology and Immunology, vol. 40, no. 9, pp. 599-605

Keywords 

Borrelia burgdorferi sensu latoRFLP16s rRNA

Abstract 

Nine Borrelia burgdorferi sensu lato isolated in Korea were subjected to genomic hybridization using 16S rRNA gene probe and specific restriction patterns (HindIII and EcoRV) led these nine Borrelia into five subtypes. The evolutionary relationships of the five isolates corresponding to five RFLP groups were measured through the sequence determination of 16S rRNA gene and phylogenetic analysis. The isolates 935T (group I), 934U and 17Y (Group IIa, IIb) were well clustered with B. garinii and B. afzelii. 5MT and 9MT strains (Group IIIa and Group IIIb) formed a common branch shared with B. afzelii cluster although the evolutionary distance was rather long. So, most of B. burgdorferi sensu lato in Korea was B. afzelii or B. afzelii-related group and some minor group such as B. garinii also existed.

ISSN 

0385-5600

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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