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Title 

Inhibition of chitin synthase II by catechins from stem bark of Taxus cuspidata

Authors 

Sung Uk KimEui Il HwangJi Youn NamKwang Hee SonSong Hae BokHong Eun KimByoung-Mog Kwon

Publisher 

Georg Thieme Verlag

Issue Date 

1999

Citation 

Planta Medica, vol. 65, no. 0, pp. 97-98

Keywords 

chitin synthaseenzyme inhibitionplant stems

Abstract 

Two flavonoids, (±)-catechin and (-)-epicatechin, were isolated from the stem bark of Taxus cuspidata by monitoring chitin synthase 11 inhibitory activity. The compounds inhibit chitin synthase II with an IC50 of 15 and 29 μg/ml, respectively and appear to be selective for chitin synthase II. They did not inhibit chitin synthase III.

ISSN 

0032-0943

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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