상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

Chitin synthase II inhibitory activity of urosolic acid, isolated from Crataegus pinnatifida

Authors 

Tae Sook JeongEui Il HwangHyang Bok LeeEun Sook LeeYoung Kook KimByung Sun MinKi Hwan BaeSong Hae BokSung Uk Kim

Publisher 

Georg Thieme Verlag

Issue Date 

1999

Citation 

Planta Medica, vol. 65, no. 3, pp. 261-263

Keywords 

crataegus pinnatifida extractCrataegusCrataegus pinnatifida

Abstract 

Two triterpenoid compounds, ursolic acid and uvaol, were isolated from Crataegus pinnatifida Bunge leaves. Ursolic acid inhibits chitin synthase II from S. cerevisiae with an IC50 value of 0.84 μ/ml and the inhibition appears to be selective for chitin synthase II, whereas uvaol has no inhibitory activity up to 280 μg/ml. Oleanolic acid, α-hederin hydrate, and betulic acid inhibited the chitin synthase II activity under the same conditions with an IC50 of 5.6, 64.3, and 98.7 μg/ml, respectively.

ISSN 

0032-0943

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)