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Title 

Acyl-CoA: cholesterol acyltransferase inhibitory activity of ginseng sapogenins, produced from the ginseng saponins

Authors 

Byoung-Mog KwonMi Kyung KimNam In BaekDong Sung KimJong Dae ParkYoung Kook KimHyung Kyu LeeShin Il Kim

Publisher 

Elsevier

Issue Date 

1999

Citation 

Bioorganic & Medicinal Chemistry Letters, vol. 9, no. 10, pp. 1375-1378

Keywords 

cholesterol acyltransferase inhibitorsaponincholesterol blood levelcholesterol metabolismginsengSapogeninsSaponinsSterol O-Acyltransferase

Abstract 

Ginseng sapogenins were produced from ginseng saponins, isolated from Korean ginseng roots. Ginseng saponins very mildly inhibited acyl- CoA:cholesterol acyltransferase (ACAT) in vitro, however, the sapogenins showed strong inhibitory activity on microsomal ACAT. Therefore, the sapogenins will be one of key ingredients of ginseng affected a lowering of the serum total cholesterol level.

ISSN 

0960-894X

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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